Naproxen thrombocytopenia
نویسندگان
چکیده
منابع مشابه
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen
In patients suspected of having druginduced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in vivo, can be the sensitizing agents, but very little is known about the specific metabolites that can cause this complicatio...
متن کاملImmune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen.
In patients suspected of having drug-induced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in vivo, can be the sensitizing agents, but very little is known about the specific metabolites that can cause this complicati...
متن کاملEnantioselective hydrolysis of racemic naproxen nitrile and naproxen amide to S-naproxen by new bacterial isolates.
Bacteria were enriched from soil samples with succinate as a carbon source and racemic naproxen nitrile [2-(6-methoxy-2-naphthyl)propionitrile] as sole source of nitrogen. Since naproxen nitrile was only poorly soluble in water media amended with different water-immiscible organic phases were used for the enrichments. With pristane (2,6,10,14-tetramethylpentadecane) as the organic phase two bac...
متن کاملNaproxen-associated vasculitis.
Three cases of digital vasculitis attributable to naproxen ingestion are reported. The vasculitic changes were reversed by withdrawal of the drug. These three cases emphasize the need to consider drug sensitivity as a cause of unexplained digital vascular lesions.
متن کاملJaundice associated with naproxen.
Hepatic injury in association with naproxen therapy is described and documented by liver biopsy in one patient. Histological findings were consistent with a drug-induced hepatitis, and cessation of therapy led to reversal of the clinical and biochemical changes. Circumstantial evidence is in favour of a hypersensitivity response to the drug rather than direct hepatotoxicity. Increased awareness...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 1989
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.2830310119